Chromatin Immunoprecipitation Sequencing (Chip-Seq)
Description
ChIP-Sequencing (ChIP-Seq) is widely used to analyze protein interaction with DNA. We have extensive experience supporting partners across the world with their ChIP-Seq research needs. ChIP-Sequencing is widely used to analyze protein interaction with DNA. It combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify binding sites of DNA-associated proteins, and can be used to precisely map global binding sites for any protein of interest. ChIP sequencing offers higher resolution and more precise and abundant information in comparison to array-based ChIP-chip approaches.
In addition to clean data output, BGI offers a range of standard, advanced and customized bioinformatics pipelines for your ChIP-Seq analysis project. We have particular expertise in the correlation analysis of RNA-Seq differential expression genes and ChIP-Seq peak related genes. Contact us for a no obligation discussion with our project experts.
Sequencing Service Specification
The ChIP-Seq Service will be performed with BGI’s DNBSEQ sequencing technology, featuring combinatorial probe-anchor synthesis (cPAS) and DNA Nanoballs (DNB) technology[1] for superior data quality.
Services Specification
- 50bp Single-end sequencing reads
- Standard output 20 Million reads per sample
- Clean data and bioinformatics analysis are available in standard file formats
- Available data storage and bioinformatics applications
- Cloud-based data storage and delivery system
Turn Around Time
- Typical 25 working days from sample QC acceptance to final data delivery
- Expedited services are available
Sample Requirements
ChIP-ed DNA: Amount ≥ 10ng, Concentration ≥ 1 ng/µl
ChIP 15 µl -ed DNA (human sample only): Amount ≥ 5ng, Concentration ≥ 1 ng/µl
